Vaughn was born in Minneapolis, Minnesota, the son of Vernon Lindsay Vaughn, a salesman for a meat company, and Sharon Eileen (née DePalmo), a Canadian-born real estate agent and stockbroker once ranked as one of the United States' top money managers by Bloomberg Wealth Manager magazine. He has two older sisters, Valerie and Victoria. He was raised "both Protestant and Catholic" by his Catholic Read more...

In 1988, Vaughn was cast in a Chevrolet television commercial, and subsequently moved to Hollywood. Although he appeared in the 1989 season of the television series, China Beach and in three CBS Schoolbreak Specials (in 1990), he was a struggling actor and faced many rejections. His first film role was 1993's Rudy, but Vaughn did not receive wider success until his role in 1996's Swingers. Swingers Read more...

Vaughn dated two of his The Break-Up co-stars: actress Joey Lauren Adams during the filming of 1999's A Cool, Dry Place and Jennifer Aniston between 2005 and 2006. His relationship with Aniston began the summer after her separation from husband Brad Pitt. Due to the media firestorm surrounding it, along with Pitt's relationship with Angelina Jolie, Vaughn and Aniston's relationship was showered Read more...