Her past television credits include co-hosting PM Magazine, Entertainment Tonight and hosting Extra, as well as Leeza, her own NBC/syndicated talk show, which ran from January 1994 to September 2000. In the 1990s she was the co-host of John and Leeza, a talk show with former co-host of Entertainment Tonight, John Tesh. She has also guest starred on several shows, including The Geena Davis Show, The Simple Life, and The Simpsons. She played a television reporter in the Robocop films and had a small role as a reporter in Soapdish. She has also been in lifetime's what should you Do?

In 1988, she was also the host of the "Telethon" show on New Zealand's TVNZ network, which she hosted alongside Christopher Quinten, who she later married (see below). In addition to her television and radio career, Gibbons has received the Congressional Horizon Award for her work on children's issues.

On February 20, 2007, the ABC television network announced that Gibbons would be a participant