Her private life has become a favorite subject of paparazzi and gossip magazines, and her breakup from actor Mauricio Islas was well published. She was involved in a mini scandal in Puerto Rico, where a camera man filmed her while she was leaving a swimming pool, which supposedly caused Fonsi's brother to allegedly beat the photographer up. Because of this, there is a claim in court against the Fonsi brothers.

López is the wife of fellow Puerto Rican singing super star Luis Fonsi. In 2006, Lopez and Fonsi announced they would be getting married during the summer of that year. They were married on June 3, 2006 in Puerto Rico.